Category: Everyday Science | Last updated: 2026-09-18
The positive predictive value of a test depends heavily on:
A) Test sensitivity alone
B) The prevalence of the disease in the population being tested
C) Specificity alone
D) Sample size only
Explanation
PPV = TP/(TP+FP). Even highly specific tests have low PPV in low-prevalence populations (many false positives relative to true positives). Bayesian reasoning: prior probability matters.