Category: Everyday Science | Last updated: 2026-09-18

The positive predictive value of a test depends heavily on:

A) Test sensitivity alone
B) The prevalence of the disease in the population being tested
C) Specificity alone
D) Sample size only

Explanation

PPV = TP/(TP+FP). Even highly specific tests have low PPV in low-prevalence populations (many false positives relative to true positives). Bayesian reasoning: prior probability matters.

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